Comparative analysis of varicella-zoster virus and herpes simplex virus 1 interaction with epidermal terminal differentiation in primary human keratinocytes models of differentiation
Cristina Tommasi, Geonhee Kim, Aoxin Liu, Andriani Drousioti, Olumide Kayode Ogunbiyi, Oscar Enrique Torres Montaguth, Afshin Mosahebi, Judith Breuer
This study compares how VZV and HSV-1 interact with epidermal differentiation in primary human keratinocytes, showing that viral replication is restricted in differentiated cells, with VZV more affected than HSV-1.
bioRxiv · May 21, 2026 · PreprintMicrobiology