2P-NucTag: on-demand phototagging for molecular analysis of functionally identified cortical neurons
Jingcheng Shi, Boaz Nutkovich, Dahlia Kushinsky, Bovey Y. Rao, Stephanie A. Herrlinger, Emmanouil Tsivourakis, Tiberiu S. Mihaila, Margaret E. Conde Paredes, Katayun Cohen-Kashi Malina, Cliodhna K. O’Toole, Hyun Choong Yong, Brynn M Sanner, Angel Xie, Erdem Varol, Attila Losonczy, Ivo Spiegel
The paper introduces 2P-NucTag, a method to label and profile functionally distinct neurons in vivo, revealing gene expression differences between place and silent hippocampal pyramidal neurons.
Neuron · Apr 2, 2026Peer-reviewedNeuroscience