Cisplatin drives mitochondrial dysregulation in sensory hair cells
David S. Lee, Angela D. Schrader, Jiaoxia Zou, Wee Han Ang, Mark E. Warchol, Lavinia Sheets
This study shows cisplatin accumulates in hair cell mitochondria and causes dysregulation, linking mitochondrial dysfunction to cisplatin-induced hearing loss.
bioRxiv · Jan 29, 2024 · PreprintNeuroscience