Mechanisms of superior respiratory IgA responses against SARS-CoV-2 after mucosal vaccination
Jinyi Tang, Arka Sen Chaudhuri, Panke Qu, Pei Li, Yajie Liu, Yue Wu, Kristin Wavell, MarthaJoy M. Spano, In Su Cheon, Chaofan Li, Jane Yu, Harish Narasimhan, Mohd Arish, Wei Qian, Gislane de Almeida Santos, , Jie Sun
This study investigates respiratory IgA responses after SARS-CoV-2 infection, vaccination, or hybrid immunity, showing that mucosal booster vaccination enhances IgA and protective immunity.
bioRxiv · Sep 22, 2025 · PreprintImmunology