Yajie Liu

IFN-inducible Human Phospholipid Scramblase 1 (PLSCR1) ProteinRestricts HIV-1 Infection by Inhibiting Membrane Fusion

This study identifies PLSCR1 as a host restriction factor that inhibits HIV-1 and related viruses by blocking membrane fusion during entry, independent of interferon signaling.

Mechanisms of superior respiratory IgA responses against SARS-CoV-2 after mucosal vaccination

This study investigates respiratory IgA responses after SARS-CoV-2 infection, vaccination, or hybrid immunity, showing that mucosal booster vaccination enhances IgA and protective immunity.

Immune Evasion, Cell-Cell Fusion, and Spike Stability of the SARS-CoV-2 XEC Variant: Role of Glycosylation Mutations at the N-terminal Domain

This study examines how glycosylation mutations in the NTD of the SARS-CoV-2 XEC variant affect neutralizing antibody responses, cell-cell fusion, and spike stability.

Neutralization and Stability of JN.1-derived LB.1, KP.2.3, KP.3 and KP.3.1.1 Subvariants

This study evaluates neutralization, infectivity, and stability of JN.1-derived SARS-CoV-2 subvariants, finding that DelS31 mutation in the NTD reduces nAb titers, impairs infectivity, and increases spike stability.

Distinct Patterns of SARS-CoV-2 BA.2.87.1 and JN.1 Variants in Immune Evasion, Antigenicity and Cell-Cell Fusion

This study compares immune evasion, antigenicity, and cell-cell fusion properties of SARS-CoV-2 BA.2.87.1 and JN.1 variants, finding BA.2.87.1 shows less neutralization escape and higher infectivity than JN.1 and XBB.1.5.