BioinformaticsbioRxivPreprint
High-Throughput Screening Reveals Potential Inhibitors Targeting Trimethoprim-Resistant DfrA1 Protein in Klebsiella pneumoniae and Escherichia coli
Soharth Hasnat, Soaibur Rahman, Meherun Binta Alam…·Tofazzal Islam
This study identifies six potential inhibitors of the DfrA1 protein through high-throughput screening of 3,601 compounds, with DC4 and DC6 showing superior efficacy compared to the control drug.
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