The Rab GTPase Ypt1p governs the activation of Unfolded Protein Response (UPR) in Saccharomyces cerevisiae by promoting the preferential nuclear degradation of pre-HAC1 mRNA
Sunirmal Paira, Anish Chakraborty, Biswadip Das
The paper shows Ypt1p regulates UPR by controlling pre-HAC1 mRNA decay through nuclear localization and interactions with the NNS/CTEXT complex.
bioRxiv · Aug 18, 2022 · PreprintMolecular Biology