14-3-3 epsilon inhibits premature centriole disengagement by inhibiting the activity of Plk1 and Separase.
M. Jaiswal, Akshay Karn, Aparna Das, Anisha Kumari, Shilu Tiwari, Sorab Nariman Dalal
This study shows that 14-3-3 epsilon inhibits centriole disengagement by suppressing Plk1 and Separase activity, leading to reduced cell proliferation and cell death.
Journal of Cell Science · Jun 27, 2025Peer-reviewedCell Biology