BiophysicsbioRxivPreprint
Translational T-box riboswitches bind tRNA by modulating conformational flexibility
Eduardo Campos-Chavez, Sneha Paul, Zunwu Zhou…·Alfonso Mondragón
This study uses single-molecule FRET to analyze the binding mechanism of the Mycobacterium tuberculosis IleS T-box riboswitch, revealing a two-step model and the role of specific sequences in conformational flexibility and tRNA recognition.
DOI 10.1101/2024.02.02.578613