Functional NHE1 Expression is Critical to Blood Brain Barrier Integrity and Sumatriptan Blood to Brain Uptake
Erika Liktor‐Busa, Kiera T. Blawn, Kathryn L. Kellohen, Beth M. Wiese, Vani Verkhovsky, Jared Wahl, Anjali Vivek, Seph M. Palomino, Thomas P. Davis, Todd W. Vanderah, Tally M. Largent‐Milnes
This study investigates the role of NHE1 in BBB integrity during CSD events and its impact on drug uptake, finding that NHE1 disruption affects BBB function and sumatriptan penetration.
PLoS ONE · May 29, 2020Peer-reviewedNeuroscience