Author

Ankit Garg

Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21205

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Biophysics· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

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Kory J. LavineiD· 1 shared Lina GreenbergiD· 1 shared Michael J. GreenbergiD· 1 shared Rui Zhang· 1 shared Silvia JanseniD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiophysics

Kory J. LavineORCID

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1 paper

Recent·Most cited

Dilated cardiomyopathy-associated skeletal muscle actin (ACTA1) mutation R256H disrupts actin structure and function and causes cardiomyocyte hypocontractility

Ankit Garg, Silvia Jansen, Lina Greenberg, Rui Zhang, Kory J. Lavine, Michael J. Greenberg

This study shows that the ACTA1 R256H mutation disrupts actin structure and function in cardiomyocytes, leading to reduced contractility and a likely causative role in dilated cardiomyopathy.

bioRxiv · Mar 10, 2024Biophysics