Selectivity profile of the poly(ADP-ribose) polymerase (PARP) inhibitor, A-966492
Ann-Gerd Thorsell, Herwig Schüler
This study evaluates the selectivity of A-966492, a PARP inhibitor, against six PARP family enzymes and finds its selectivity for PARP1 and PARP2 is intermediate between veliparib and niraparib.
bioRxiv · Mar 23, 2017 · PreprintCancer Biology