Mutagenesis study of a Bacteriophytochrome - insights for the development of labels for optical imaging.
Azeem A. Mohammed, David Wiesner, Anna Dachs, Elias Wippermann, Simon Göllner, Stephanie Willeit, Uwe Klemm, Selina Schulz, Bjarne Perleberg, John J. Galligan, Elsa Charas Rodrigues, Isabella Rembeck, Axel Duerkop, Vasilis Ntziachristos, Till Rudack, André C. Stiel
The paper studies a BphP from Rhizobium etli to identify variants suitable for optical imaging, including a bright far-red-shifted BphP and a photoswitching BphP for background suppression in vivo.
bioRxiv · Mar 4, 2026 · PreprintBiochemistry