Till Rudack

This study uses NMR to measure nanosecond methyl dynamics in the RNA exosome core, showing that relaxation-violated coherence transfer experiments can quantify side chain order parameters in large protein complexes.

kontakteUR transforms structural coordinates into a chemically informed contact space to analyze biomolecular interactions and their changes, enabling systematic comparison and functional insights.

The paper uses cryo-electron tomography to study structural changes in mitochondrial protein biogenesis under proteostatic stress, revealing remodeling of cristae and mHsp60 conformation.

The paper studies a BphP from Rhizobium etli to identify variants suitable for optical imaging, including a bright far-red-shifted BphP and a photoswitching BphP for background suppression in vivo.

This paper presents a computational method to calculate retinal isomerization in real time, revealing an asymmetric potential energy landscape and branched photocycle that align with experimental data.

The paper uses NMR and simulations to study dynamic motions in the eukaryotic RNA exosome complex, revealing conformational changes and a flexible plug region that blocks RNA pathways.

The paper predicts high-accuracy vibrational spectra from molecular structures using simulations and evaluates methods for IR-based structure determination.

This study determines the structure of two late-stage PSII assembly intermediates, revealing how Psb32 and Psb27 regulate OEC maturation and Mn4O5Ca cluster preparation.

The Chlamydomonas psb28 mutant shows severe PSII assembly defects, and complexome profiling identifies TEF5 as a novel PSII assembly factor involved in CP47 assembly.

This study characterizes AkVAL, a bistable opsin from the flashlight fish, showing its ability to control neuronal activity and body movement in response to light cycles, suggesting its potential as an optogenetic tool.

The paper validates a computational prediction of an antibody mutation that abolishes antigen binding using experimental methods, demonstrating its utility in Alzheimer's disease diagnostics.