Microfilaremic loiasis is associated with T cell hyporesponsiveness against SARS CoV-2
Maximilian Augé-Stock, Dearie Glory Okwu, Ayong More, Anna Doralt, Rodrigue Bikangui, Ismaël Pierrick Mikelet Boussoukou, Kirsten Alexandra Eberhardt, Maren Sandkuhl, Rella Zoleko Manego, Ghyslain Mombo‐Ngoma, Matthew McCall, Minka Breloer, Meral Esen, Marylyn M. Addo, Bertrand Lell, , Maria Sophia Mackroth
This study finds that microfilaremic loiasis is associated with reduced IFN-γ T cell responses to SARS-CoV-2, while IgG responses remain similar across infection statuses.
PLoS neglected tropical diseases · Oct 1, 2026Peer-reviewedImmunology