Human Fcγ-receptors selectively respond to C-reactive protein (CRP) isoforms
Anna Henning, Johanna Seer, Johannes Zeller, Karlheinz Peter, Haizhang Chen, Julia Thomé, Philipp Kolb, Steffen U. Eisenhardt, Katja Hoffmann, Hartmut Hengel
This study identifies which Fcγ-receptors respond to CRP isoforms and shows that pCRP* is the main activator, differing from IgG-Fc interactions.
Frontiers in Immunology · May 19, 2025Peer-reviewedImmunology