Calculating sample size for identifying cell subpopulation in single-cell RNA-seq experiments
Kyung In Kim, Ahrim Youn, Mohan T. Bolisetty, Anna Karolina Palucka, Joshy George
The paper develops a statistical method to calculate the optimal number of cells needed to detect a rare subpopulation in scRNA-seq experiments, validated using dendritic cell and monocyte data.
bioRxiv · Jul 18, 2019 · PreprintBioinformatics