Repeated administration of 2-hydroxypropyl-β-cyclodextrin (HPβCD) attenuates the chronic inflammatory response to experimental stroke
Danielle A. Becktel, Jacob C. Zbesko, Jennifer B. Frye, Amanda G. Chung, Megan Hayes, Kylie Calderon, Jeffrey W. Grover, Anna Li, Frankie G. Garcia, Marco A. Tavera-Garcia, Rick G. Schnellmann, Hsin-Jung Joyce Wu, Thuy‐Vi V. Nguyen, Kristian P. Doyle
This study shows that repeated HPβCD treatment reduces chronic inflammation and cognitive decline after stroke by modulating lipid metabolism and immune responses.
Journal of Neuroscience · Nov 24, 2021Peer-reviewedNeuroscience