Complex system modelling reveals oxalate homeostasis is driven by diverse oxalate-degrading bacteria
Sromona Mukherjee, Carlos Batagello, Ava Adler, Jose Agudelo, Anna M. Zampini, Mangesh Vasant Suryavanshi, Andrew H. Nguyen, Teri J. Orr, M. Denise Dearing, Manoj Monga, Aaron W. Miller
The paper models oxalate homeostasis using a complex systems framework, showing that microbiome composition and metabolic redundancy affect oxalate-degrading bacteria's efficacy in clinical trials.
bioRxiv · Oct 28, 2024 · PreprintMicrobiology