Genetic Substrates of Brain Vulnerability and Resilience in Aging APOE2 Mice
Ali Mahzarnia, Hae Sol Moon, Jacques Andrew Stout, Robert J. Anderson, Madison Strain, Jessica T. Tremblay, Zay Yar Han, Andrei Niculescu, Anna MacFarlane, Jasmine King, Allison E. Ashley‐Koch, Darin P. Clark, Michael William Lutz, Alexandra Badea
This study investigates how APOE2 alleles affect brain vulnerability and resilience in aging mice, identifying age-related brain atrophy, sex differences, and gene expression changes.
bioRxiv · Dec 12, 2022 · PreprintNeuroscience