Author

Darin P. Clark

Duke UniversityORCID 0000-0002-8496-4565Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexandra BadeaiD· 1 shared Ali MahzarniaiD· 1 shared Allison E. Ashley‐KochiD· 1 shared Andrei Niculescu· 1 shared Anna MacFarlane· 1 shared Hae Sol MooniD· 1 shared Jacques Andrew StoutiD· 1 shared Jasmine King· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alexandra BadeaORCID

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1 paper

Recent·Most cited

Genetic Substrates of Brain Vulnerability and Resilience in Aging APOE2 Mice

Ali Mahzarnia, Hae Sol Moon, Jacques Andrew Stout, Robert J. Anderson, Madison Strain, Jessica T. Tremblay, Zay Yar Han, Andrei Niculescu, Anna MacFarlane, Jasmine King, Allison E. Ashley‐Koch, Darin P. Clark, Michael William Lutz, Alexandra Badea

This study investigates how APOE2 alleles affect brain vulnerability and resilience in aging mice, identifying age-related brain atrophy, sex differences, and gene expression changes.

bioRxiv · Dec 12, 2022 · PreprintNeuroscience