Sperm AluY Epimutations in Male Partners of Couples with Unexplained Recurrent Pregnancy Loss
Elango Kamaraj, Jordan Moore, Mykle Keni, Anna Terry, Nastaran Salehisedeh, Neha Biju, Martha Susiarjo, Jonathon T. Hill, Timothy G. Jenkins, Winifred Mak
The paper identifies AluY epimutations in sperm from men with unexplained recurrent pregnancy loss, showing they are enriched in hypomethylated regions and linked to genes involved in early development.
bioRxiv · Sep 25, 2026 · PreprintDevelopmental Biology