Congenital CMV infection drives oligoclonal expansion of cytotoxic γδ T cells from early fetal progenitors
Justine Levan, Anna V. Vaaben, Jessica Tsui, Brittany R. Davidson, Meagan E. Olive, Perri C. Callaway, Catherine B. Nguyen, Mikias Ilala, Ravi K. Patel, Riana D. Hunter, Gabriela K. Fragiadakis, Alexis J. Combes, Felistas Nankya, Grant Dorsey, Abel Kakuru, , Margaret E. Feeney
The paper shows congenital CMV infection leads to oligoclonal expansion of cytotoxic γδ T cells with fetal-like TCR features in neonates.
bioRxiv · Nov 20, 2025 · PreprintImmunology