Jessica L. Tsui

This study develops an iSCST framework for FFPE biopsies, identifying colitis-associated cell networks and VDZ response signatures in IBD patients.

The paper compares mouse and human tumor microenvironments, identifying conserved and species-specific features in immune composition and gene expression programs.

The paper shows congenital CMV infection leads to oligoclonal expansion of cytotoxic γδ T cells with fetal-like TCR features in neonates.

This study shows that activating the STING pathway in osteosarcoma leads to tumor regression and immune memory, suggesting it as a therapeutic target.

This study shows that a short-term high-fat diet during the onset of psoriasis worsens disease severity through immune system changes, even after returning to a normal diet.

The paper identifies space-time gene expression patterns in healing wounds and finds their conservation in tumors, revealing multicellular coordination and gene program activation.