Early onset memory deficit of WMI rats compared to their nearly isogenic WLIs is reversed by enriched environment in females
Michelle T. Ji, Katherine J. Przybyl, Aspen M. Harter, Mariya Nemesh, Sophia T. Jenz, Anna Yamazaki, Chris Kim, Megan K. Mulligan, Hao Chen, Eva E. Redei
This study shows that enriched environment reverses early-onset memory deficits in middle-aged WMI female rats, with associated changes in estradiol and mitochondrial function.
Genes Brain & Behavior · Jun 1, 2025Peer-reviewedAnimal Behavior & Cognition