Yorkie-independent negative feedback couples Hippo pathway activation with Kibra degradation
Sherzod A. Tokamov, Ting Su, Anne Ullyot, Richard G. Fehon
The paper shows the Hippo pathway downregulates Kibra levels through SCFSlimb-mediated ubiquitination, independent of Yorkie, to control tissue growth.
eLife · Feb 8, 2021Peer-reviewedDevelopmental Biology