Richard G. Fehon

aPKC and F-actin Dynamics Promote Hippo Pathway Polarity in Asymmetrically Dividing Neuroblasts

This study shows that Kibra and Salvador polarize to the apical cortex of neuroblasts, and their localization is driven by aPKC activity and F-actin dynamics.

Dachsous and Fat coordinately repress the Dachs-Dlish-Approximated complex to control growth

This study investigates how Dachsous and Fat regulate the core complex to control growth in Drosophila by modulating its stability and localization.

Yorkie-independent negative feedback couples Hippo pathway activation with Kibra degradation

The paper shows the Hippo pathway downregulates Kibra levels through SCFSlimb-mediated ubiquitination, independent of Yorkie, to control tissue growth.

Rho1 activation recapitulates early gastrulation events in the ventral, but not dorsal, epithelium of Drosophila embryos

This study shows that Rho1 activation in Drosophila embryos induces different deformations in ventral and dorsal epithelia, revealing that ventral-specific factors are needed for full gastrulation.