The Aryl Hydrocarbon Receptor senses the Henna pigment Lawsone and mediates Yin-Yang effects on skin homeostasis
Laura Lozza, Pedro Moura-Alves, Teresa Domaszewska, Carolina Lage Crespo, Ioana Streata, Annika Kreuchwig, Marina Bechtle, Marion Klemm, Ulrike Zedler, Silviu Ungureanu Bogdan, Ute Guhlich-Bornhof, Anne-Britta Koehler, Manuela Staeber, Hans-Joachim Mollenkopf, Robert Hurwitz, , Stefan H.E. Kaufmann
This study shows that Lawsone, a Henna pigment, activates the AhR receptor in skin cells, with both beneficial and harmful effects depending on the physiological context.
bioRxiv · Nov 4, 2018 · PreprintCell Biology