A new conditional mouse model for Cre-mediated restoration of Hprt1 expression during brain development
Jurjan R.J. Havelaar, Anneke Fuß, Sandra Blaess, Sharon M. Kolk, Jasper E. Visser
This paper introduces a conditional Hprt1 mouse model to study the effects of gene restoration during brain development and demonstrates its utility in understanding reversibility in genetic disorders.
bioRxiv · Sep 17, 2026 · PreprintNeuroscience