Role of Immune Checkpoint Proteins in Idiopathic Pulmonary Fibrosis
David M Habiel, Milena Espindola, Chris Kitson, Anthony Azzara, Ana Lucia Coelho, Cory M Hogaboam
This study investigates immune checkpoint proteins in IPF, finding that CTLA-4 limits profibrotic T cells while PD-1 and PD-L1 are elevated in IPF lungs.
bioRxiv · Aug 8, 2017 · PreprintImmunology