Size-dependent increase in RNA Polymerase II initiation rates mediates gene expression scaling with cell size
Xi-Ming Sun, Anthony Bowman, Miles Priestman, François Bertaux, Amalia Martínez-Segura, Wenhao Tang, Chad Whilding, Dirk Dormann, Vahid Shahrezaei, Samuel Marguerat
The paper investigates how RNA Polymerase II initiation rates scale with cell size in fission yeast, showing that RNAPII is a limiting factor for transcriptional scaling.
Current Biology · Feb 13, 2020Peer-reviewedMolecular Biology