Author

Anton Goloborodko

Primary ORCID profile (0000-0002-2210-8616 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Anton GoloborodkoiD2 papers · Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA)

Biology Disciplines

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Biophysics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:yeast· 1

Frequent Co-Authors

John F. Marko· 2 shared Geoffrey Fudenberg· 1 shared Leonid A. Mirny· 1 shared Leonid Mirny· 1 shared Maxim V. Imakaev· 1 shared Oliver J. Rando· 1 shared Tsung-Han S. Hsieh· 1 shared

Activity by Year

2015-2016 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 7 mutual co-author links

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2 shared papersBiophysics

John F. Marko

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3 papers

Recent·Most cited

Micro-C XL: assaying chromosome conformation at length scales from the nucleosome to the entire genome

Tsung-Han S. Hsieh, Geoffrey Fudenberg, Anton Goloborodko, Oliver J. Rando

The paper introduces Micro-C XL, an improved 3C technique for chromosome conformation analysis, showing increased signal-to-noise and revealing both short-range and higher-order genomic structures in yeast.

bioRxiv · Aug 24, 2016 · PreprintGenomics

Compaction and segregation of sister chromatids via active loop extrusion

Anton Goloborodko, Maxim V. Imakaev, John F. Marko, Leonid A. Mirny

This study shows loop extrusion by condensins can compact, segregate, and disentangle chromosomes, explaining chromosome condensation and topology control.

bioRxiv · Jan 30, 2016Biophysics

Mitotic chromosome compaction via active loop extrusion

Anton Goloborodko, John F. Marko, Leonid Mirny

This study demonstrates that chromosome compaction during cell division occurs through active loop extrusion by molecular machines, matching experimental observations of loop size, compaction, and morphology.

bioRxiv · Jun 29, 2015Biophysics