Characterization of spe-40/Fam187 identifies a deeply conserved sperm protein at the C. elegans fertilization synapse
Jeyashree Nathan Elango, Isaac H. Shin, Anushree Gurjar, Amber R. Krauchunas
This study identifies SPE-40/FAM187 as a conserved sperm protein essential for fertilization in C. elegans, showing that its mutation causes sub-fertility without affecting sperm production or motility.
bioRxiv · May 18, 2026 · PreprintDevelopmental Biology