Author

Anya T. Applebaum Licht

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Anne E. van VlimmereniD· 1 shared Deepti KaranduriD· 1 shared Neel H. ShahiD· 1 shared Ziyuan JiangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Anne E. van VlimmerenORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

BiochemistryProtein SciencePeer-reviewedNov 12, 2025

The pathogenic E139D mutation stabilizes a non-canonical active state of the multi-domain phosphatase SHP2

Anne E. van Vlimmeren, Ziyuan Jiang, Deepti Karandur…·Neel H. Shah

This study identifies a novel active conformation of SHP2 stabilized by the E139D mutation, which alters phosphoprotein binding preferences compared to canonical hyperactive mutants.

2 citations

humanprotein structure

𝕏 PostBluesky