REBASTINIB, OLVEREMBATINIB, AND NAS-181 INHIBIT MYCOBACTERIUM ABSCESSUS BY DISRUPTING MYCOTHIOL HOMEOSTASIS
David Serrano, Elena M. Duarte, Arjun Mehta, Robert J. Collins, AP Sugunan
This study identifies rebastinib, olverembatinib, and NAS-181 as potential drugs that inhibit Mycobacterium abscessus by disrupting mycothiol homeostasis, showing efficacy in vitro and in vivo.
bioRxiv · Aug 22, 2025 · PreprintMicrobiology