Electronic Cigarette Aerosol Exposure Induces Airway Remodeling in 3D Human Tracheobronchial Epithelial Tissues: From Goblet Cell Hyperplasia to Squamous Metaplasia
Rattapol Phandthong, Edgar Rolon, Brianna Ramirez, Mohamad Kudsi, Audrey Choi, Arash Tamasbi, Teresa Martinez, Prue Talbot
This study shows that EC aerosol exposure leads to airway epithelial remodeling in 3D human tissues, progressing from goblet cell hyperplasia to squamous metaplasia over three weeks.
bioRxiv · Oct 30, 2025 · PreprintPharmacology & Toxicology