Prue Talbot

This study shows SARS-CoV-2 pseudoparticles infect human embryonic stem cell-derived ectoderm more than other germ layers, due to multiple entry pathways, high TMPRSS2, and reduced glycocalyx.

This study investigates hydroxyacetone's toxicological effects on human airway epithelial cells, finding mitochondrial dysfunction, oxidative stress, and cytoskeletal disruption at concentrations found in e-cigarette aerosols.

This study shows human neural stem cells are susceptible to SARS-CoV-2 infection, with Omicron variants using endocytosis and glycosylation levels affecting entry.

This study shows that EC aerosol exposure leads to airway epithelial remodeling in 3D human tissues, progressing from goblet cell hyperplasia to squamous metaplasia over three weeks.

This study shows that WS-23, a synthetic coolant in e-cigarettes, disrupts human embryonic cell development by inhibiting pluripotency and inducing endoderm differentiation at nanomolar concentrations.

This study compares the chemicals, cytotoxicity, and risk of aerosols from ultrasonic cigarettes to heated-coil pod-style e-cigarettes, finding no significant reduction in harm.