Long-Term Intestinal Epithelial Remodeling Induced by Acute Protein-Energy Malnutrition
Fenja Amrei Schuran, Neha Mishra, Víctor A. López-Agudelo, Nina Sommer, Joana P. Bernardes, Alesia Walker, Finn Hinrichsen, Ting Gong, Felix Gilbert, Lena Schröder, Archana Bhardwaj, Sven Künzel, Saskia Weber‐Stiehl, Go Ito, Florian Tran, , Philip C Rosenstiel
This study investigates long-term intestinal epithelial changes after acute protein-energy malnutrition using multi-omics approaches and identifies microbial lipid metabolites and epigenetic factors as key drivers of persistent Paneth cell dysfunction.
bioRxiv · Oct 20, 2025 · PreprintImmunology