Go Ito

Fetal reversion from diverse lineages sustains the intestinal stem cell pool and confers stress resilience

This study shows that fetal reversion from diverse lineages sustains the intestinal stem cell pool and enhances stress resilience through bidirectional interconversion between CBCs and revSCs.

Long-Term Intestinal Epithelial Remodeling Induced by Acute Protein-Energy Malnutrition

This study investigates long-term intestinal epithelial changes after acute protein-energy malnutrition using multi-omics approaches and identifies microbial lipid metabolites and epigenetic factors as key drivers of persistent Paneth cell dysfunction.

Genome-wide analysis of 944,133 individuals provides insights into the etiology of hemorrhoidal disease

This study performs a genome-wide association analysis of hemorrhoidal disease in 944,133 individuals, identifying 102 risk loci and linking them to vascular and tissue development pathways.

Depletion of erythropoietic miR-486-5p and miR-451a improves detectability of rare microRNAs in peripheral blood-derived small RNA sequencing libraries

The paper presents a method to deplete dominant miRNAs from blood-derived RNA samples, improving detectability of low-abundance miRNAs in small RNA sequencing.