Alesia Walker

This study investigates long-term intestinal epithelial changes after acute protein-energy malnutrition using multi-omics approaches and identifies microbial lipid metabolites and epigenetic factors as key drivers of persistent Paneth cell dysfunction.

The paper integrates multi-omics data from mice to identify molecular features linked to aging-related cognitive decline, highlighting systemic inflammation and microbiome-driven gut-brain axis dysfunction.

This study uses multi-omics and metabolic modeling in mice to show that aging reduces host-microbiome metabolic interactions, affecting key host pathways involved in intestinal barrier function and homeostasis.