Transcription factor collaboration enables precise T cell state engineering
Rachel E. Savage, Christian D. McRoberts Amador, Conrad Hock, Ruochi Zhang, Hung‐Che Kuo, Aretha Gao, Max A. Horlbeck, Charles A. Gersbach, Jason Daniel Buenrostro
The paper identifies transcription factor collaborations that shape CD8+ T cell states and demonstrates how engineering these interactions can influence cell fate for therapeutic applications.
bioRxiv · Apr 22, 2026 · PreprintGenomics