Author

Ari Löytynoja

Primary ORCID profile (0000-0001-5389-6611 · 12 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Ari LöytynojaiD12 papers · University of Helsinki

Biology Disciplines

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Bioinformatics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:non-human primate· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

Alan Medlar· 2 shared Andreia Miraldo· 1 shared Chunxiang Li· 1 shared Laura Laakso· 1 shared Nick Goldman· 1 shared

Activity by Year

2016-2016 · peak 3/yr

Co-Author Collaboration Network

5 top collaborators · 4 mutual co-author links

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2 shared papersBioinformatics

Alan Medlar

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Short template switch events explain mutation clusters in the human genome

Ari Löytynoja, Nick Goldman

The paper introduces a mutation model based on template switching during replication to explain complex mutation clusters in the human genome and finds thousands of such events in human and chimp evolution.

bioRxiv · Sep 27, 2016Genomics

Co-estimation of Phylogeny-aware Alignment and Phylogenetic Tree

Chunxiang Li, Alan Medlar, Ari Löytynoja

The paper introduces Canopy, a tool for parallelized alignment that reduces guide tree biases, showing it produces more accurate alignments than existing methods.

bioRxiv · Sep 26, 2016 · PreprintBioinformatics

Glutton: large-scale integration of non-model organism transcriptome data for comparative analysis

Alan Medlar, Laura Laakso, Andreia Miraldo, Ari Löytynoja

Glutton processes transcriptome assemblies for comparative analysis by reconstructing gene-level alignments and orthologs, improving accuracy over heuristic methods.

bioRxiv · Sep 26, 2016 · PreprintBioinformatics