Karyopherin α2 is a maternal effect gene required for early embryonic development and female fertility in mice
Franziska Rother, Reinhard Depping, Elena Popova, Stefanie Hügel, Ariane Heiler, Enno Hartmann, Michael Bäder
This study shows that KPNA2 deficiency in mice causes embryonic arrest at the 2-cell stage and disrupts genome activation and nuclear translocation of Nucleoplasmin 2.
The FASEB Journal · Apr 24, 2024Peer-reviewedDevelopmental Biology