Shared and unique consequences of Joubert Syndrome gene dysfunction on the zebrafish central nervous system
Alexandra R. Noble, Markus Masek, Claudia Hofmann, Arianna Cuoco, Tamara D. S. Rusterholz, Hayriye Özkoç, Nadja R. Greter, Ian G. Phelps, Nikita Vladimirov, Sepp Kollmorgen, Esther T. Stoeckli, Ruxandra Bachmann‐Gagescu
The paper investigates the effects of Joubert Syndrome gene dysfunction in zebrafish, finding altered brain cilia, changes in neuron-related gene expression, and abnormal swimming behavior despite normal brain structure.
Biology Open · Oct 14, 2024Peer-reviewedNeuroscience