Nikita Vladimirov

This paper introduces an optical modification using a K-mirror and electrically tunable lens to enable fast two-photon imaging along curved planes in biological structures.

This study shows FoxP transcription factors are essential for peripheral nervous system development in chicken embryos, affecting axon guidance and neural crest cell migration.

aDISCO enables 3D microscopy of large archival FFPE human tissue blocks, revealing subtle pathologies in focal cortical dysplasia through deep-learning analysis.

The paper develops a deep learning pipeline for analyzing 3D collagen architecture in cleared fibrotic tissues using optimized clearing, imaging, and a U-Net model.

The paper introduces Pythia, a tool that uses deep learning to predict CRISPR/Cas9 integration and editing outcomes by leveraging non-random DNA repair patterns.

The paper investigates the effects of Joubert Syndrome gene dysfunction in zebrafish, finding altered brain cilia, changes in neuron-related gene expression, and abnormal swimming behavior despite normal brain structure.

The paper introduces an improved open-source light-sheet microscope, mesoSPIM, with enhanced resolution, throughput, and compatibility with cleared samples.

The paper identifies a brainstem circuit in larval zebrafish that integrates optic flow to maintain positional homeostasis by modulating cerebellar activity.