High Resolution Solvated Models Reveal Mechanisms of Allosteric Activation of mTORC1 by RHEB
Prithwish Ghosh, Arijit Maity, Kutti Ragunath Vinothkumar, Ravindra Venkatramani
The paper uses computational methods to generate high-resolution models of mTORC1 with RHEB, revealing structural changes that enable allosteric activation.
bioRxiv · Mar 19, 2026 · PreprintBioinformatics