Ravindra Venkatramani

The paper uses computational methods to generate high-resolution models of mTORC1 with RHEB, revealing structural changes that enable allosteric activation.

This study shows mTOR regulates epithelial apical projections through S6K1-RhoA and aPKC-Lgl2 pathways in zebrafish.

This paper develops a fluorescent probe to track PI(4,5)P2 dynamics in neurons, revealing that hallucinogenic ligands at the 5-HT2A receptor cause slower initial PI(4,5)P2 depletion compared to non-hallucinogenic ligands.

The paper uses molecular dynamics simulations to show that ATP binding free energy in CDK1 is affected by acetylation at the active site and reveals non-local entropy changes linked to protein-protein interactions.