Kutti Ragunath Vinothkumar

Structures of Multiple Peptide Resistance Factor from Pseudomonas aeruginosa

This study presents cryoEM structures of PaMprF from Pseudomonas aeruginosa, revealing its dimeric architecture and dynamic elements involved in lipid modification.

Biochemical and structural characterisation of MprF homologue,LpiA from Agrobacterium

The paper characterizes the structure and function of the MprF homologue LpiA from Agrobacterium, revealing its dimeric structure and the role of conserved residues in substrate binding.

Epistatic interaction between ribosome-associated Era GTPase and stringent response regulator RelA modulates bacterial cell growth and dormancy

The paper investigates how the interaction between Era GTPase and RelA regulates bacterial dormancy exit and growth by modulating ribosome function and stringent response.

High Resolution Solvated Models Reveal Mechanisms of Allosteric Activation of mTORC1 by RHEB

The paper uses computational methods to generate high-resolution models of mTORC1 with RHEB, revealing structural changes that enable allosteric activation.

Distinct filament morphology and membrane tethering features of the dual FtsZs in Odinarchaeota

This study compares two FtsZ isoforms in Odinarchaeota, revealing distinct filament structures and membrane tethering mechanisms, highlighting evolutionary diversity in the FtsZ-Tubulin superfamily.

Analysis of ribosomes from the Wild-type and FMR1 knockout human embryonic stem cells

This study analyzes ribosomes from wild-type and FMR1 knockout human embryonic stem cells, revealing altered translation rates and rRNA methylation patterns linked to FMRP's role in translational regulation.

Molecular determinants of Neu5Ac binding to tripartite ATP independent periplasmic (TRAP) transporter

The paper reports the structures of SiaQM from Fusobacterium nucleatum with and without Neu5Ac, revealing interactions and transport mechanisms.

Duox generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts

The paper shows Duox-generated ROS activates ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts through a non-canonical mechanism.