Leishmania-infected human dendritic cells clear their intracellular parasites by a mechanism involving the cytolytic effector molecules granzyme B and granulysin
Ibrahim Mohamed Azzouz, Renato B. Baleeiro, Lydon Wainaina Nyambura, Arkadi Kundik, Peter Walden
This study shows human dendritic cells destroy Leishmania parasites using granzyme B and granulysin, unlike macrophages which are infected and ruptured.
bioRxiv · Oct 15, 2026 · PreprintImmunology