Comparative genomics of Cryptococcus and Kwoniella reveals pathogenesis evolution and contrasting karyotype dynamics via intercentromeric recombination or chromosome fusion
Marco A. Coelho, Marcia David Palma, Terrance Shea, Katharine Bowers, Sage M. Smith, Arman W. Mohammad, Andreas Gnirke, Andrey M. Yurkov, Minou Nowrousian, Sheng Sun, Christina A. Cuomo, Joseph Heitman
The paper compares the genomes of pathogenic and non-pathogenic Cryptococcus species with related Kwoniella species, revealing gene gains/losses and chromosome fusion mechanisms linked to pathogenesis.
PLoS Biology · Jun 6, 2024Peer-reviewedGenomics